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Fosamax is a bisphosphonate drug used for osteoporosis and several other bone diseases. It is marketed alone as well as in combination with vitamin D under the name Fosavance.

What You Should Know Before Taking Fosamax

What You Should Know Before Taking FosamaxFosamax is a bisphosphonate drug used for osteoporosis and several other bone diseases. It is marketed alone as well as in combination with vitamin D under the name Fosavance.Side-effectsGI tract: most prominent are harmless side effects such as mild nausea, dyspepsia, abdominal cramps, flatulence, diarrhea, or obstipation. A severe side effect is an ulceration of the esophagus caused by alendronate, which may require hospitalization and intensive treatment. Gastric and duodenal ulceration. General: infrequent cases of skin rash, rarely manifesting as Stevens-Johnson syndrome and toxic epidermal necrolysis, eye problems (uveitis, scleritis) and generalized muscle, joint, and bone pain (rarely severe) have been seen. In laboratory tests decreased calcium and phosphate values may be obtained but reflect action of the drug and are harmless. Osteonecrosis of the jaw, a recognised side-effect of bisphosphonates. DosageProphylaxis of osteoporosis in women: 5-10mg daily or 35-70mg weekly. Therapy of osteoporosis in women and men : 10mg daily or 70mg weekly. Osteoporosis under corticosteroids: 5mg daily or 35mg weekly in men and premenopausal women or those receiving concomitant HRT. In postmenopausal women not receiving HRT the recommended dose is 10mg daily or 70mg weekly. Paget's Disease: 40mg daily for 6 months. The drug is to be taken only upon rising for the day with plenty of water. Stand, walk or sit 30 minutes afterwards to avoid esophageal damage. At least 30 minutes should be waited before meals or other beverages than water are taken in.InteractionsMilk, diet and drugs containing high amounts of calcium, magnesium or aluminium (antacids): the resorption of alendronate is decreased. At least half an hour should pass after intake of alendronate before taking the supplement or drug. Highly active vitamin D analogues or fluorides: no data is available. Concomitant treatment should be avoided. The additional beneficial effect of HRT (hormone replacement therapy) with estrogens/progestins or raloxifene in postmenopausal women remains to be elucidated, but no interactions have been seen. The combination is therefore possible. Intravenous ranitidine increases the oral bioavailability of alendronate. No clinical consequences are known. The combination of NSAIDS and alendroate increases the risk of gastric ulcers. Both these drugs have the potential to irritate the upper gastro-intestinal mucosa. Does Merck have a patent on this drug? Yes, but the patent is set to expire in 2008 and Merck has lost a series of appeals to block a generic version of the drug from being certified by the US FDA.Now you can understand why there's a growing interest in Fosamax. When people start looking for more information about Fosamax, you'll be in a position to inform them with facts.DisclaimerThe information presented here should not be interpreted as medical advice. Please consult your physician before taking Fosamax or any other drug.Permission is granted to reprint this article as long as no changes are made, and the entire resource box is included.

Vitamin A And Vitamin E For Acne

Vitamin A And Vitamin E For Acne

In the fight against acne, vitamins A and E both act fairly similarly and both have great advantages for preventing its outbreak. Needless to say, getting proper amounts of these vitamins into your body everyday is crucial for maintaining clear, healthy skin and for helping to prevent acne from becoming a problem.Vitamin A fights acne initially by helping to strengthen the protective tissue of the skin. Additionally, it reduces sebum (oil) production in the skin. This combination helps the skin to become more capable of fighting acne and also this healthy skin, with less oil, is less likely to suffer from acne breakouts. Furthermore, Vitamin A is a very strong antioxidant which helps to rid the body, including the skin, of harmful toxins and free radicals, therefore helping to clear the skin of many problems, including acne. Vitamin A is usually taken in conjunction with carotenoids which enhances its effects against acne.Vitamin E is also an antioxidant. Although not as strong of one as Vitamin A, Vitamin E still does help to rid the skin of toxins which can lead to acne and helps to clear up existing acne. Vitamin E also promotes tissue repair and healing of the skin, two important aspects that help to both strengthen the skin and also to prevent damage caused by acne to become permanent. Additionally, Vitamin E prevents cell damage by inhibiting the oxidation of lipids (fats) and the formation of free radicals.As can be seen, both vitamins have fairly similar methods of assisting in the fight against acne. Both help to strengthen the skin and healthier, stronger skin is less prone to acne. Both are also antioxidants and help to clear the skin of acne and prevent future breakouts. The difference is that Vitamin A reduces oil production and Vitamin E promotes tissue repair and healing. In combination, these vitamins are extremely effective in combating acne.Both Vitamin A and Vitamin E are extremely important vitamins and a deficiency in either of them can lead to acne. Consuming healthy amounts of these vitamins every day can help to fight existing acne and also to enable to body to better prevent further acne breakouts from occurring. Put plainly, both of these vitamins should be involved in any methods used to combat acne and should be heavily considered when looking for acne fighting vitamin supplements.

Drugs For Treating Aids May Prevent People From Catching Aids

Drugs For Treating Aids May Prevent People From Catching Aids

In one of the most promising developments in more than 20 years, scientists claim that drugs used to control HIV/AIDS in patients may also be effective in preventing the disease in the first place.The drugs in question are tenofovir (Viread) and emtricitabine, or FTC (Emtriva), sold in combination as Truvada by Gilead Sciences Inc. Gilead is the California company best known for inventing Tamiflu.Previous research has been aimed at finding a vaccine against HIV/AIDS, with the intention of conditioning the immune system against the disease. But these drugs work differently. They simply keep the virus from reproducing, and have already been used successfuly by health care workers to prevent them from being infected by the virus carried by patients.This approach to fighting HIV/AIDS has been tempting researchers for many years, but has only recently become feasible as preventative drugs have been developed that are safe for non-infected persons to take. Previous drugs had unreasonable effects for uninfected persons.That situation changed when Tenofovir came on the market in 2001. Tenofovir is powerful and safe, and it only has to be taken once a day. It also does not interact with other medicines or birth control pills, and manifests less drug resistance than other AIDS medications.** Monkey studies show exciting resultsA major study by the CDC (Centers for Disease Control and Prevention) in Atlanta, Georgia involved six macaques. The monkeys were given a combination of Tenofovir and FTC and then administered a deadly combination of monkey and human AIDS viruses. They were given the viruses in rectal doses to simulate contact between gay men. Each was given 14 weekly exposures of the virus, and none of the monkeys became infected. In a control group which did not receive the drugs, all but one got the disease, normally after just two exposures. The scientists then stopped giving the drugs to the test group to see if the prevention was only temporary. The results were equally impressive. None of the monkeys contracted the disease. "We're now four months following the animals with no drug, no virus. They're uninfected and healthy," reported a CDC researcher.Now other research teams are pushing to have this drug combination tested on humans. A $29 million CDC study of drug users in Botswana will now be switched to this new drug combination.Another study of 400 heterosexual women in Ghana by the Family Health Initiative, and funded by the Bill and Melinda Gates Foundation, is studying the effects of tenofovir alone.But several other studies have failed to materialize because studies of this nature immediately raise suspicions that scientists are using local people as guinea pigs. The fear is that they will intentionally expose the test subjects to the virus.The cost of tenofovir and Truvada also make testing difficult. In African countries condoms are now liberally donated by companies, aid groups, UN agencies, and western governments. While the drugs are relatively cheap, the cost remains an impediment.Nevertheless researchers have been reinvigorated by the stunning results out of Atlanta, and new tests are going ahead in pockets of interest around the world.

What Is Rhinoplasty?

What Is Rhinoplasty?

Rhinoplasty, commonly called a nose job, is a type of cosmetic surgery designed to repair or reshape the nose. As one of the most prominent features on your face, your nose has a large bearing on your appearance and can impact how you feel about yourself. Individuals who are displeased with the size or shape of the nose can benefit from rhinoplasty because of the opportunity it offers to completely alter the appearance of the nose. Rhinoplasty has the ability to increase or reduce the size of the nose in its entirety, removing a bump, altering the shape of the bridge or the tip of your nose, narrowing the nostril openings, and modifying the angle between your nose and your lips. Rhinoplasty cannot be successfully performed until the nose has stabilized and nasal bone has stopped growing. This typically occurs around age 14 to 15 in girls and age 15 to 16 in boys. Any surgery performed before this point runs the risk of having to be redone once nasal growth has ceased, since the nose has the potential to continue to change and develop until that point. Rhinoplasty is occasionally performed on younger children in the case of severe trauma to the face, so that the nose can be restored as close as possible to its original shape and size.Most rhinoplasty procedures are performed on an outpatient basis under general anesthesia. There are exceptions to this rule, though. Patients undergoing severe reconstructive surgery may be monitored overnight to ensure that no complications arise. Individuals seeking to have their nose set after a bad break will occasionally receive local anesthetic only. During the procedure the cosmetic surgeon makes an incision either inside the nostrils or through the columella, the external strip of tissue that separates the nostrils. The skin is then separated away from the framework of the nose itself so the doctor can access the underlying cartilage. In order to reshape the nose, the soft flexible cartilage and bone are manipulated into the proper position and shape. Depending on the desired results, tissue may be removed or added to change the angle or contour of the nose. A chisel or file may be used during the procedure, most frequently to remove a hump from the bridge of the nose. Once the nose has been sculpted into the desired shape, the skin is resituated and the nose is splinted to protect it. Nasal pads may be used for the first few days following the surgery to pack the nose and protect the delicate septum.Rhinoplasty, as with all other surgeries, is not risk-free. In addition to the standard bruising and swelling, patients should be aware of a number of potential side-effects that could result from the procedure. These include an infection of the nose, nosebleeds, numbness, scarring, and a reaction to the anesthesia. Some patients report the bursting of small blood vessels on the surface of the skin and hematomas, or collections of blood that pool under the skin. The possibility also exists that a follow-up procedure will be necessary in order to remedy an over-correction or under-correction of the nose.When successfully performed by a highly-qualified surgeon, rhinoplasty can dramatically improve the appearance of your nose and improve your self-confidence. If you are considering rhinoplasty and would like more information about this procedure, contact a reputable cosmetic surgeon in your area and arrange for a personal consultation.

Six Great Tips For Dry Eyes

Faulty tear glands may not be something you think about until you experience the aching, itching and stinging that can accompany dry eyes. Dry eyes can be more than a minor burden; serious dryness can lead to abrasions of the cornea and possibly blindness if left untreated.More than 3.2 million women and 1.6 million men (in the United States) over the age of 50 experience the symptoms of dry eye. For some the experience is occasional, while others must learn to deal with constant dryness. The causes for dry eyes are varied. They can include decongestants, antihistamines, blood pressure medicine, winter winds, air conditioning and indoor heating. Whatever the cause, there is a variety of natural remedies and preventable measures you can undertake to help your eyes stay moist.Smoking: Simple...Quit. Smoking has been shown to dry out your eyes. In addition, smoking increases the risk of cataracts, glaucoma, and macular degeneration.Automobile Air vents: Vents pointed at your face and eyes can quickly drain the moisture in your eyes. Make sure to aim the vents away from your eyes or wear sunglasses for protection.Omega-3: A recent study out of Japan has found that omega-3 supplementation could help prevent dry-eye syndrome.Vitamin A: Taking a vitamin A supplement or eating vitamin A rich foods such as salmon or eggs can help keep your eyes moist.Blink: In the electronic age, many of us spend a good deal of time staring at a computer screen. This can irritate even mild cases of dry eyes. When you are concentrating, you tend not to blink as much. Not blinking as frequently will make eye moisture evaporate rapidly. Ever so often, look away from your computer (or television) and take a blink break. Your eyes will thank you.Humidify: Low moisture levels can dry your eyes fast. The winter can be especially drying during sleep. If possible, get a humidifier for the areas in which you spend a lot of time.Your eyes are one of your most prized possessions. Think for a second what life would be like without them. It is important not to take them for granted. I hope the above remedies help, if not or if the problem persists, get to an eye doctor.

Points To Remember About A Spastic Colon

Did you know that nearly half of the population of the developed countries like USA and Canada suffer from the disorders caused by spastic colon? It is a chronic health problem that affects a number of people which is far greater than the number of population suffering from diabetes, asthma or depression.At this point you are wondering what "spastic colon" actually is. Let us put it like this: It is a kind of dysfunction of colon in which the passage of wastes through the intestine is obstructed due to the changes in the normal pattern of muscular contractions of colon that mobilize wastes. Spastic colon is typically a functional disorder and not a disease, which implies that bowel movement is not occurring in a manner it should have been. The result is either constipation or diarrhea or in many cases a bout of both in alternate succession. The other symptoms include abdominal pain, bloating, painful bowel movement and stool full of mucus. In women, there is a close relation between menstruation and attack of spastic colon. It has led the medical practitioners establish a correlation between hormonal changes and irritable bowel syndrome.Dealing with spastic colon is rather easy; you have to incorporate little changes in your lifestyle. To begin with, bring in little changes in your food habit to get rewarded by a problem free bowel movement. First of all try to understand which foods trigger off the symptoms and religiously avoid them. Generally cut down on the fat content in your diet and go for baked or micro waved foods instead of those fried or roasted. If you have a fetish for milk products, then consumes only skimmed or semi skimmed milk.More importantly, take the foods that are rich in fiber and increase the proportion of fresh vegetables and whole grain cereals in your diet. Another simple rule is: divide your entire meal of the day in small portions and eat more often but small amount at a time. Yoghurt provides a natural solution to those suffering from static colon, as yoghurt containing helpful bacteria aids in the digestive process.Second important point in dealing with static colon is to managing stress. Under the circumstances of twenty first century living, stress management may sound rather an impossible task. But if you want to get a problem free bowel habit, you have to learn to cope up with stress factors through such practices as meditation, aerobics exercise with music, relaxing over the weekends completely cutting off from the work related anxieties and availing other relaxation therapies.If things go really bad, go and see the doctor at earliest. The faster you address the problem with proper medication, earlier you get relief from irregular bowel syndrome. But above all you should stick to a healthy lifestyle; that is the best guarantee for having a problem free colon and overall health.

Summary

Fosamax is a bisphosphonate drug used for osteoporosis and several other bone diseases. It is marketed alone as well as in combination with vitamin D under the name Fosavance.